4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde

This compound is a synthetic small molecule belonging to the class of substituted anilinoquinolines. It acts as an inhibitor of mitogen-activated protein kinase 14 (MAPK14), also known as p38 alpha MAP kinase, which is a serine/threonine kinase involved in cellular responses to pro-inflammatory cytokines and physical stress. The compound has been studied structurally in complex with human p38 MAPK14 and is referenced in structural biology databases but does not have any approved medical indications or clinical trial data available. Its primary use appears to be as a research tool for studying the inhibition of MAPK14/p38 signaling pathways[1][6].

Other names

7-substituted 4-anilinoquinoline, 31